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Literature summary for 2.7.1.4 extracted from
- Kinetic characteristics and regulatory mechanisms of glucokinase and fructokinase from Zymomonas mobilis (1982), Eur. J. Appl. Microbiol. Biotechnol., 14, 241-246.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ADP | - |
Zymomonas mobilis |  |
| AMP | inhibitory at low and stimulatory at high ATP concentration | Zymomonas mobilis | |
| ATP | - |
Zymomonas mobilis | |
| D-fructose | weak | Zymomonas mobilis | |
| D-glucose | - |
Zymomonas mobilis | |
| D-glucose 6-phosphate | - |
Zymomonas mobilis | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Zymomonas mobilis | |
| 0.07 | - |
D-fructose | with ATP as cosubstrate, pH 7.4, 30°C | Zymomonas mobilis | |
| 0.16 | - |
ATP | - |
Zymomonas mobilis | |
| 0.16 | - |
ATP | pH 7.4, 30°C | Zymomonas mobilis | |
| 0.25 | - |
ITP | - |
Zymomonas mobilis | |
| 0.25 | - |
ITP | pH 7.4, 30°C | Zymomonas mobilis | |
| 0.26 | - |
UTP | - |
Zymomonas mobilis | |
| 0.26 | - |
UTP | pH 7.4, 30°C | Zymomonas mobilis | |
| 0.54 | - |
D-fructose | with UTP as cosubstrate, pH 7.4, 30°C | Zymomonas mobilis | |
| 1.25 | - |
D-fructose | with ITP as cosubstrate, pH 7.4, 30°C | Zymomonas mobilis | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + D-fructose | Zymomonas mobilis | - |
ADP + D-fructose 6-phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Zymomonas mobilis | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + D-fructose | - |
Zymomonas mobilis | ADP + D-fructose 6-phosphate | - |
? | |
| ATP + D-fructose | specific for fructose | Zymomonas mobilis | ADP + D-fructose 6-phosphate | - |
? | |
| ATP + D-fructose | specific for fructose and ATP | Zymomonas mobilis | ADP + D-fructose 6-phosphate | - |
? | |
| CTP + D-fructose | no activity | Zymomonas mobilis | CDP + D-fructose 6-phosphate | - |
? | |
| ITP + D-fructose | - |
Zymomonas mobilis | IDP + D-fructose 6-phosphate | - |
? | |
| additional information | no activity with GTP | Zymomonas mobilis | ? | - |
? | |
| additional information | no substrate: D-mannose | Zymomonas mobilis | ? | - |
? | |
| additional information | no substrate: D-glucose | Zymomonas mobilis | ? | - |
? | |
| UTP + D-fructose | - |
Zymomonas mobilis | UDP + D-fructose 6-phosphate | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
- |
Zymomonas mobilis |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| AMP | inhibitory at low and stimulatory at high ATP concentration | Zymomonas mobilis | |
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