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Information on EC 2.7.1.4 - fructokinase
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2.7.1.4 fructokinaseSpecify your search results
Word Map
- 2.7.1.4
-
cyclosporine
-
rejection
-
allograft
- tacrolimus
- steroid
-
opioids
- rapamycin
- keratitis
- enkephalin
- bowel
- naloxone
- forskolin
- corneal
- creatinine
- mycophenolate
-
nephrotoxicity
- met-enkephalin
- mofetil
-
postoperative
- calcineurin
-
orthotopic
- invertase
-
opiate
- morphine
-
trough
- glucokinase
- azathioprine
- sirolimus
-
heterotopic
-
immunophilins
-
posttransplant
-
d-ala2
-
readable
-
allotransplantation
- beta-endorphin
-
readability
- tachykinins
- medicine
- synthesis
-
retransplantation
-
donor-specific
-
keratoplasty
- fractalkine
-
actuarial
- hexokinases
- fructose-1-phosphate
- methionine-enkephalin
-
steroid-resistant
The enzyme appears in viruses and cellular organisms
Synonyms
fk, fructokinase, mdfrk2, hore_18220, mdfrk1, putative fructokinase, atfrk6, atfrk7, vc-fk, atp:d-fructose 6-phosphotransferase, 
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
cscK
D-fructokinase
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-
-
-
D-fructose(D-mannose)kinase
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-
-
-
FK
-
-
-
-
FK1
FK2
FRK
Frk1
Frk2
Frk3
Frk4
fructokinase
kinase, fructo- (phosphorylating)
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-
-
-
MEALZv4_0616
putative fructokinase
ROK FK
Vc-FK
YdhR
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REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
ATP + D-fructose = ADP + D-fructose 6-phosphate
-
-
-
-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
phospho group transfer
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-
-
-
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PATHWAY SOURCE
PATHWAYS
BRENDA
KEGG
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SYSTEMATIC NAME
IUBMB Comments
ATP:D-fructose 6-phosphotransferase
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CAS REGISTRY NUMBER
COMMENTARY
9030-51-7
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
fructose metabolism
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
to enter metabolism, fructose is phosphorylated by a fructokinase
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-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
no activity with ribose, xylose, fucose, glucose, tagatose or arabinose
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
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highly specific for D-fructose
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-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
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specific for fructose
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-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
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fructose metabolism
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
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high specificity for fructose but no affinity for glucose
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-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
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-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
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the first step in fructose metabolism is mediated by fructokinase
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-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
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highly specific for D-fructose, both isoforms
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-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
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-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
fructose metabolism
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
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sucrose to starch synthetic pathway
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-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
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-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
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higher affinity for ATP than for other NTPs
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-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
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best phosphate donor for isozymes FK-II and FK-III
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-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
fructose metabolism
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
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sucrose to starch synthetic pathway
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-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
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specific for fructose
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?
ATP + D-fructose
ADP + D-fructose 6-phosphate
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inducible enzyme
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-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
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highly specific for D-fructose, minor products are D-fructose 2-phosphate and D-fructose-3 phosphate
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
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specific for fructose
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
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specific for fructose and ATP
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?
ATP + D-glucose
ADP + D-glucose 6-phosphate
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isoform FRK1, 1.6% of activity with D-fructose, isoform FRK2, 7.8% of activity with D-fructose
-
-
?
ATP + D-glucose
ADP + D-glucose 6-phosphate
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isoenzyme FK-I and FK-II less than 5% of the activity with fructose
-
-
?
ATP + D-mannose
ADP + D-mannose 6-phosphate
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D-fructose and D-mannose phosphorylated at equivalent rates
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?
ATP + D-mannose
ADP + D-mannose 6-phosphate
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isoform FRK1, 2.2% of activity with D-fructose, isoform FRK2, 2.4% of activity with D-fructose
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-
?
ATP + D-mannose
ADP + D-mannose 6-phosphate
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isoenzyme FK-I and FK-II low activity, less than 5% of D-fructose, FK-III no activity
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
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6% of activity with ATP
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
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higher activity than with ATP
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-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
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40% of the activity with ATP
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-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
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isoform FRK1, 35% of activity with ATP, isoform FRK2, 83% of activity with ATP
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-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
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30% of the activity with ATP
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
-
16% of activity with ATP
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
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7.4times higher activity than with ATP
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-
?
dATP + D-fructose
dADP + D-fructose 6-phosphate
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90% of the activity with ATP
-
-
?
dATP + D-fructose
dADP + D-fructose 6-phosphate
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90% of the activity with ATP
-
-
?
dATP + D-fructose
dADP + D-fructose 6-phosphate
-
80% of the activity with ATP
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-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
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23% of activity with ATP
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
30% of the activity with ATP
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
30% of the activity with ATP
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
isoform FRK1, 23% of activity with ATP, isoform FRK2, 135% of activity with ATP
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
best phosphate donor for isozyme FK-I
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
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50% of the activity with ATP
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
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62% of activity with ATP
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
3fold higher activity than with ATP
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-
?
ITP + D-fructose
IDP + D-fructose 6-phosphate
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78% of activity with ATP
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-
?
ITP + D-fructose
IDP + D-fructose 6-phosphate
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25% of the activity with ATP
-
-
?
ITP + D-fructose
IDP + D-fructose 6-phosphate
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25% of the activity with ATP
-
-
?
ITP + D-fructose
IDP + D-fructose 6-phosphate
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60% of the activity with ATP
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-
?
ITP + D-fructose
IDP + D-fructose 6-phosphate
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73% of activity with ATP
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-
?
TTP + D-fructose
TDP + D-fructose 6-phosphate
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0.18% of activity with ATP
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-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
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higher activity than with ATP
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-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
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80% of the activity with ATP
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-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
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80% of the activity with ATP
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-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
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isoform FRK1, 39% of activity with ATP, isoform FRK2, 84% of activity with ATP
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-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
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20% of the activity with ATP
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-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
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16% of activity with ATP
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