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Literature summary for 2.7.1.218 extracted from
- Identification of a pathway for the utilization of the amadori product fructoselysine in Escherichia coli (2002), J. Biol. Chem., 277, 42523-42529 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli | Escherichia coli |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.018 | - |
N6-(D-fructosyl)-L-lysine | pH 7.1, 30°C | Escherichia coli |  |
| 0.05 | - |
ATP | pH 7.1, 30°C | Escherichia coli | |
| 24 | - |
1-deoxy-1-morpholinofructose | pH 7.1, 30°C | Escherichia coli | |
| 80 | - |
fructosylglycine | pH 7.1, 30°C | Escherichia coli | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 28000 | - |
gel filtration | Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | P45543 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 1-deoxy-1-morpholinofructose | poor substrate | Escherichia coli | ADP + 6-phospho-1-deoxy-1-morpholinofructose | - |
? | |
| ATP + fructosylglycine | poor substrate | Escherichia coli | ADP + 6-phospho-D-fructosylglycine | - |
? | |
| ATP + N6-(D-fructosyl)-L-lysine | - |
Escherichia coli | ADP + N6-(6-phospho-D-fructosyl)-L-lysine | - |
? | |
| additional information | enzyme catalyzes the ATP-dependent phosphorylation of fructoselysine to fructoselysine 6-phosphate | Escherichia coli | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 28332, calculated | Escherichia coli |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| frlD | - |
Escherichia coli |
| YhfQ | - |
Escherichia coli |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | Escherichia coli can grow on fructoselysine as an energetic substrate at a rate of about one-third of that observed with glucose. Extracts of cells grown on fructoselysine catalyze the phosphorylation of fructoselysine and a delayed formation of glucose 6-phosphate from this substrate. Enzymes of the Yhf operon are responsible for the reactions | Escherichia coli |
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