Information on EC 2.7.1.218 - fructoselysine 6-kinase

for references in articles please use BRENDA:EC2.7.1.218
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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
2.7.1.218
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RECOMMENDED NAME
GeneOntology No.
fructoselysine 6-kinase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + N6-(D-fructosyl)-L-lysine = ADP + N6-(6-phospho-D-fructosyl)-L-lysine
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
fructoselysine and psicoselysine degradation
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SYSTEMATIC NAME
IUBMB Comments
ATP:D-fructosyl-L-lysine 6-phosphotransferase
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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UniProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + 1-deoxy-1-morpholinofructose
ADP + 6-phospho-1-deoxy-1-morpholinofructose
show the reaction diagram
ATP + fructosyl-L-epsilon-lysine
ADP + 6-phospho-D-fructosyl-L-epsilon-lysine
show the reaction diagram
ATP + fructosyl-L-valine
ADP + 6-phospho-D-fructosyl-L-valine
show the reaction diagram
ATP + fructosylglycine
ADP + 6-phospho-D-fructosylglycine
show the reaction diagram
ATP + fructosylglycylglycine
ADP + 6-phospho-D-fructosylglycylglycine
show the reaction diagram
ATP + N6-(D-fructosyl)-L-lysine
ADP + N6-(6-phospho-D-fructosyl)-L-lysine
show the reaction diagram
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?
additional information
?
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enzyme catalyzes the ATP-dependent phosphorylation of fructoselysine to fructoselysine 6-phosphate
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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
6.5 - 47
1-deoxy-1-morpholinofructose
0.05
ATP
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pH 7.1, 30C
0.02 - 14
fructosyl-L-epsilon-lysine
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0.1 - 20
fructosyl-L-valine
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0.6 - 80
fructosylglycine
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6 - 20
fructosylglycylglycine
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0.018
N6-(D-fructosyl)-L-lysine
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pH 7.1, 30C
kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.05 - 0.14
1-deoxy-1-morpholinofructose
0.25 - 750
fructosyl-L-epsilon-lysine
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0.001 - 15
fructosyl-L-valine
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0.006 - 8.3
fructosylglycine
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0.23 - 0.83
fructosylglycylglycine
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LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
28000
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gel filtration
SUBUNITS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
monomer
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1 * 28332, calculated
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli
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