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Literature summary for 2.7.1.211 extracted from

  • Zeng, L.; Burne, R.A.
    Comprehensive mutational analysis of sucrose-metabolizing pathways in Streptococcus mutans reveals novel roles for the sucrose phosphotransferase system permease (2013), J. Bacteriol., 195, 833-843.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Streptococcus mutans serotype c P12655
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Streptococcus mutans serotype c UA159 P12655
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General Information

General Information Comment Organism
physiological function loss of phosphotransferase ScrA activity leads to growth stimulation on fructooligosaccharides, due in large part to increased expression of the fruAB (fructanase) operon. ScrA is required for activation of levD expression (a component of fructose/mannose-PTS EII permease) by sucrose through components of the LevQRST complex, but not for activation by the cognate LevQRST sugars fructose or mannose. Sucrose-dependent catabolite repression is also evident in strains containing an intact sucrose phosphotransferase system Streptococcus mutans serotype c