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Literature summary for 2.7.1.20 extracted from

  • Park, J.; Gupta, R.S.
    Adenosine kinase and ribokinase - the RK family of proteins (2008), Cell. Mol. Life Sci., 65, 2875-2896.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
inorganic phosphate stimulates Spinacia oleracea
inorganic phosphate stimulates Trypanosoma brucei
inorganic phosphate stimulates Leishmania donovani
inorganic phosphate stimulates Homo sapiens
phosphate stimulates Saccharomyces cerevisiae

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ can substitute for Mg2+ Homo sapiens
Co2+ can substitute for Mg2+ Homo sapiens
Mg2+ required Homo sapiens
Mn2+ can substitute for Mg2+ Homo sapiens
Ni2+ can substitute for Mg2+ Homo sapiens

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-
Caenorhabditis elegans
-
-
-
Drosophila melanogaster
-
-
-
Homo sapiens P55263
-
-
Leishmania donovani
-
-
-
Saccharomyces cerevisiae
-
-
-
Schizosaccharomyces pombe
-
-
-
Spinacia oleracea
-
-
-
Trypanosoma brucei
-
-
-

Subunits

Subunits Comment Organism
monomer the active form of AK is a monomer, which is composed of an alphabetaalpha sandwich domain and a smaller lid domain Drosophila melanogaster
monomer the active form of AK is a monomer, which is composed of an alphabetaalpha sandwich domain and a smaller lid domain Saccharomyces cerevisiae
monomer the active form of AK is a monomer, which is composed of an alphabetaalpha sandwich domain and a smaller lid domain Spinacia oleracea
monomer the active form of AK is a monomer, which is composed of an alphabetaalpha sandwich domain and a smaller lid domain Trypanosoma brucei
monomer the active form of AK is a monomer, which is composed of an alphabetaalpha sandwich domain and a smaller lid domain Schizosaccharomyces pombe
monomer the active form of AK is a monomer, which is composed of an alphabetaalpha sandwich domain and a smaller lid domain Leishmania donovani
monomer the active form of AK is a monomer, which is composed of an alphabetaalpha sandwich domain and a smaller lid domain Homo sapiens
monomer the active form of the enzyme is a monomer, which is composed of an alphabetaalpha sandwich domain and a smaller lid domain Arabidopsis thaliana
monomer the active form of the enzyme is a monomer, which is composed of an alphabetaalpha sandwich domain and a smaller lid domain Caenorhabditis elegans