Activating Compound | Comment | Organism | Structure |
---|---|---|---|
cardiolipin | half-maximal activation by 1 mol% | Rattus norvegicus | |
Phospholipid | activation by phospholipid is not stereospecific and is mimicked partially by fatty acids | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
dioctanoylglycerol | above 3.4 mol% | Rattus norvegicus | |
dioleoylglycerol | above 3.4 mol% | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | Km-values are 0.92 mol% for dioleoylglycerol and 3.6 mol% for dioctanoylglycerol | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | integral membrane protein | Rattus norvegicus | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Cd2+ | when Mg2+ is excluded from the assay, Cd2+ supports activity to lesser extent | Rattus norvegicus | |
Co2+ | when Mg2+ is excluded from the assay, Co2+ supports activity to lesser extent | Rattus norvegicus | |
Mg2+ | a second Mg2+ in addition to MgATP is required for activity | Rattus norvegicus | |
Mn2+ | when Mg2+ is excluded from the assay, Mn2+ supports activity to lesser extent | Rattus norvegicus | |
Zn2+ | when Mg2+ is excluded from the assay, Zn2+ supports activity to lesser extent | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1,2-dioctanoylglycerol | - |
Rattus norvegicus | ADP + 1,2-dioctanoylglycerol 3-phosphate | - |
? | |
ATP + sn-1,2-dioleoylglycerol | - |
Rattus norvegicus | ADP + sn-1,2-dioleoylglycerol 3-phosphate | - |
? | |
additional information | the enzyme is active in mixed micelles containing octyl glucoside and dioleoylglycerol | Rattus norvegicus | ? | - |
? |