Literature summary for 2.5.1.47 extracted from

Ma, W.; Wang, J.; Li, Y.; Wang, X.
Cysteine synthase A overexpression in Corynebacterium glutamicum enhances L-isoleucine production (2019), Biotechnol. Appl. Biochem., 66, 74-81 .

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Application

Application	Comment	Organism
synthesis	CysK overexpressing cells grow fast during log phase, and produce 26.5% more L-isoleucine in flask fermentation and 23.5% more L-isoleucine in fed-batch fermentation. The key genes aspC, lysC, hom, thrB, ilvA, and ilvBN involved in L-isoleucine biosynthesis are all upregulated in CysK overexpressing Corynebacterium glutamicum IWJ001. Overexpressing cells are longer and thicker than control cells, and their membrane permeability increases by 15.8% and biofilm formation ability decreases by 71.3%	Corynebacterium glutamicum

Organism

Organism	UniProt	Comment	Textmining
Corynebacterium glutamicum	-	-	-
Corynebacterium glutamicum IWJ001	-	-	-

Synonyms

Synonyms	Comment	Organism
cysK	-	Corynebacterium glutamicum

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Release 2023.1 (January 2023)