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Literature summary for 2.5.1.16 extracted from

  • Pothipongsa, A.; Jantaro, S.; Salminen, T.A.; Incharoensakdi, A.
    Molecular characterization and homology modeling of spermidine synthase from Synechococcus sp. PCC 7942 (2017), World J. Microbiol. Biotechnol., 33, 72 .
    View publication on PubMed
Search for more literature for 2.5.1.16

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Synechococcus elongatus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.02
-
 S-adenosyl 3-(methylsulfanyl)propylamine pH 7.5, 37°C Synechococcus elongatus
0.111
-
 putrescine pH 7.5, 37°C Synechococcus elongatus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
33000
-
-
 Synechococcus elongatus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl 3-(methylsulfanyl)propylamine + putrescine Synechococcus elongatus
-
 S-methyl-5'-thioadenosine + spermidine
-
 ?
S-adenosyl 3-(methylsulfanyl)propylamine + putrescine Synechococcus elongatus PCC 7942
-
 S-methyl-5'-thioadenosine + spermidine
-
 ?

Organism

Organism UniProt Comment Textmining
Synechococcus elongatus Q31QK9
-
-
Synechococcus elongatus PCC 7942 Q31QK9
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Synechococcus elongatus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl 3-(methylsulfanyl)propylamine + putrescine
-
 Synechococcus elongatus S-methyl-5'-thioadenosine + spermidine
-
 ?
S-adenosyl 3-(methylsulfanyl)propylamine + putrescine the enzyme is highly specific for putrescine as an amine acceptor. When using cadaverine or 1,6-hexanediamine, a diamine with longer chain length, there is no detectable product formation Synechococcus elongatus S-methyl-5'-thioadenosine + spermidine
-
 ?
S-adenosyl 3-(methylsulfanyl)propylamine + putrescine
-
 Synechococcus elongatus PCC 7942 S-methyl-5'-thioadenosine + spermidine
-
 ?
S-adenosyl 3-(methylsulfanyl)propylamine + putrescine the enzyme is highly specific for putrescine as an amine acceptor. When using cadaverine or 1,6-hexanediamine, a diamine with longer chain length, there is no detectable product formation Synechococcus elongatus PCC 7942 S-methyl-5'-thioadenosine + spermidine
-
 ?

Synonyms

Synonyms Comment Organism
SPDS
-
 Synechococcus elongatus
Synpcc7942_0628
-
 Synechococcus elongatus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
-
 Synechococcus elongatus

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
30 60 30°C: about 35% of maximal activity, 60°C: about 30% of maximal activity Synechococcus elongatus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
 Synechococcus elongatus

pH Range

pH Minimum pH Maximum Comment Organism
7 9 pH 7.0: about 65% of maximal activity, pH 9.0: about 75% of maximal activity Synechococcus elongatus