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Literature summary for 2.4.3.2 extracted from

  • Gu, T.J.; Gu, X.B.; Ariga, T.; Yu, R.K.
    Purification and characterization of CMP-NeuAc:GM1 (Galbeta1-4GalNAc) alpha 2-3 sialyltransferase from rat brain (1990), FEBS Lett., 275, 83-86.
    View publication on PubMed
Search for more literature for 2.4.3.2

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.065
-
 CMP-N-acetylneuraminate pH 6.5, 37°C Rattus norvegicus
75
-
 ganglioside GM1 pH 6.5, 37°C Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Rattus norvegicus 16020
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
44000
-
 x * 44000, SDS-PAGE Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
 Rattus norvegicus

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0084
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CMP-N-acetyl-beta-neuraminate + ganglioside GA1 sialylated at 61% the rate of GM1 Rattus norvegicus CMP + ganglioside GM1b
-
 ?
CMP-N-acetyl-beta-neuraminate + ganglioside GD1b sialylated at 120% the rate of GM1 Rattus norvegicus CMP + ganglioside GT1b
-
 ?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1
-
 Rattus norvegicus CMP + ganglioside GD1
-
 ?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
-
 Rattus norvegicus CMP + ganglioside GD1a i.e. ganglioside GD1a ?

Subunits

Subunits Comment Organism
? x * 44000, SDS-PAGE Rattus norvegicus