Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.4.3.2 extracted from

  • Yip, M.C.M.
    The enzymic synthesis of disialoganglioside: rat brain cytidine-5-monophospho-N-acetylneuraminic acid: monosialoganglioside (GM1) sialyltransferase (1973), Biochim. Biophys. Acta, 306, 298-306.
    View publication on PubMed
Search for more literature for 2.4.3.2

Activating Compound

Activating Compound Comment Organism Structure
Triton CF-54 activation Rattus norvegicus
Triton CF-54 activates, can partially be replaced by cutscum or Triton X-100, not by sodium taurocholate or deoxycholate, Tween 80 or cholic acid Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
CMP-N-acetylneuraminate above 0.2 M Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 Sprague-Dawley strain
-
Rattus norvegicus Sprague-Dawley
-
 Sprague-Dawley strain
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
-
 Rattus norvegicus CMP + ganglioside GD1a i.e. ganglioside GD1a ?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
-
 Rattus norvegicus Sprague-Dawley CMP + ganglioside GD1a i.e. ganglioside GD1a ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
 cacodylate buffer Rattus norvegicus