Cloned (Comment) | Organism |
---|---|
expressed in a Corynebacterium glutamicum AftA-deficient mutant strain and in Escherichia coli C43 (DE3) cells | Mycobacterium tuberculosis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | not inhibited by ethambutol | Mycobacterium tuberculosis |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | - |
- |
- |
Mycobacterium tuberculosis H37Rv | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
beta-D-arabinofuranosyl-1-monophosphoryldecaprenol + galactan | the reaction catalyzed by the enzyme is the transfer of arabinofuranose from beta-D-arabinofuranosyl-1-monophosphoryldecaprenol to galactan | Mycobacterium tuberculosis | ? | - |
? | |
beta-D-arabinofuranosyl-1-monophosphoryldecaprenol + galactan | the reaction catalyzed by the enzyme is the transfer of arabinofuranose from beta-D-arabinofuranosyl-1-monophosphoryldecaprenol to galactan | Mycobacterium tuberculosis H37Rv | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AftA | - |
Mycobacterium tuberculosis |
arabinofuranosyltransferase A | - |
Mycobacterium tuberculosis |
Rv3792 | - |
Mycobacterium tuberculosis |
General Information | Comment | Organism |
---|---|---|
malfunction | a deletion of the AftA gene leads to complete absence of arabinose resulting in a truncated cell wall structure possessing only a galactan core with a concomitant loss of cell wall-bound mycolates | Mycobacterium tuberculosis |
physiological function | the enzyme is involved in cell wall arabinan biosynthesis | Mycobacterium tuberculosis |