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Literature summary for 2.4.2.29 extracted from
- Crystal structure of the human tRNA guanine transglycosylase catalytic subunit QTRT1 (2018), Biomolecules, 8, 81 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21(DE3)-STAR cells | Homo sapiens |
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| apoenzyme and in complex with queuine, sitting or hanging drop vapor diffusion method, using 100 mM Tris pH 7.8, 200 mM KBr, 200 mM KSCN, 3% (w/v) polyglutamic acid-LM, 5% (w/v) PEG 4000 | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| guanine34 in tRNA + queuine | Homo sapiens | - |
queuine34 in tRNA + guanine | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q9BXR0 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| His-Talon column chromatography and Superdex S200 gel filtration | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| guanine34 in tRNA + queuine | - |
Homo sapiens | queuine34 in tRNA + guanine | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| heterodimer | - |
Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| QTRT1 | catalytic subunit | Homo sapiens |
| queuine tRNA-ribosyltransferase subunit 1 | - |
Homo sapiens |
| TGT | - |
Homo sapiens |
| tRNA guanine transglycosylase | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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