Cloned (Comment) | Organism |
---|---|
CGT gene is cloned, sequenced and characterized, cell-specific and highly time-regulated expression of the gene | Mus musculus |
cloning and characterization of the CGT gene, chromosomal localization as a single-copy gene to 4q26 | Homo sapiens |
cloning of the full-length CGT cDNA, open reading frame of 1623 bp encodes a 541 amino acids core protein | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
endoplasmic reticulum | translation product with N-terminal 20 amino acids signal sequence, C-terminal 23 amino acids transmembrane domain and KKVK endoplasmic reticulum retention signal | Rattus norvegicus | 5783 | - |
membrane | - |
Homo sapiens | 16020 | - |
membrane | with C-terminal 23 amino acids transmembrane domain | Rattus norvegicus | 16020 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
64000 | - |
x * 64000 | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | - |
? | - |
? | |
additional information | Rattus norvegicus | - |
? | - |
? | |
additional information | Mus musculus | key enzyme in the biosynthesis of cerebrosides and sulfatides, cell-specific and highly time-regulated expression of the CGT gene is thought to play an important role in oligodendrocyte and Schwann cell differentiation | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | - |
Homo sapiens |
glycoprotein | high mannose glycoprotein | Rattus norvegicus |
glycoprotein | translation product with 3 putative N-glycosylation sites | Rattus norvegicus |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Mus musculus | - |
brain | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | - |
Homo sapiens | ? | - |
? | |
additional information | - |
Rattus norvegicus | ? | - |
? | |
additional information | key enzyme in the biosynthesis of cerebrosides and sulfatides, cell-specific and highly time-regulated expression of the CGT gene is thought to play an important role in oligodendrocyte and Schwann cell differentiation | Mus musculus | ? | - |
? | |
UDPgalactose + 2-(2-hydroxyacyl)sphingosine | - |
Mus musculus | 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine + UDP | - |
? | |
UDPgalactose + 2-(2-hydroxyacyl)sphingosine | - |
Homo sapiens | 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine + UDP | - |
? | |
UDPgalactose + 2-(2-hydroxyacyl)sphingosine | - |
Rattus norvegicus | 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine + UDP | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 64000 | Rattus norvegicus |