Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus fumigatus | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
CsmA | - |
Aspergillus fumigatus |
CsmB | - |
Aspergillus fumigatus |
General Information | Comment | Organism |
---|---|---|
physiological function | in the conidia, chitin content in the cell wall of a mutant strain lacking activity of isoform csmA is less than half the amount found in the parental strain. The isoform csmB mutant strain and the isoform csmA/csmB double mutant strain do not show any modification of chitin content in their conidial cell walls. In contrast to the hydrophobic conidia of the parental strain, conidia of all of the chitin synthase mutants are hydrophilic due to the presence of an amorphous material covering the hydrophobic surface-rodlet layer. The deletion of chitin synthase genes also results in an increased susceptibility of resting and germinating conidia to echinocandins | Aspergillus fumigatus |