Application | Comment | Organism |
---|---|---|
medicine | ATP citrate synthase inhibition by RNAi or the chemical SB-204990 limits in vitro proliferation and survival of tumor cells displaying aerobic glycolysis | Homo sapiens |
medicine | ATP citrate synthase inhibition by RNAi or the chemical SB-204990 limits in vitro proliferation and survival of tumor cells displaying aerobic glycolysis. The same treatments also reduce in vivo tumor growth and induce differentiation | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
SB-204990 | - |
Homo sapiens | |
SB-204990 | - |
Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-549 cell | - |
Homo sapiens | - |
K-562 cell | - |
Homo sapiens | - |
PC-3 cell | - |
Homo sapiens | - |
SKOV-3 cell | - |
Homo sapiens | - |