Literature summary for 2.3.2.29 extracted from

Graciet, E.; Hu, R.; Piatkov, K.; Rhee, J.; Schwarz, E.; Varshavsky, A.
Aminoacyl-transferases and the N-end rule pathway of prokaryotic/eukaryotic specificity in a human pathogen (2006), Proc. Natl. Acad. Sci. USA, 103, 3078-3083.

Search for more literature for 2.3.2.29

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli KPS22 cells	Vibrio vulnificus

Protein Variants

Protein Variants	Comment	Organism
C18S	inactive	Vibrio vulnificus
Y170F	the mutant loses 90% of wild type enzyme activity	Vibrio vulnificus
Y205F	the mutant loses 90% of wild type enzyme activity	Vibrio vulnificus
Y58F	the mutant loses 70-80% of wild type enzyme activity	Vibrio vulnificus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
L-leucyl-tRNALeu + N-terminal L-aspartyl-[protein]	Vibrio vulnificus	-	tRNALeu + N-terminal L-leucyl-L-aspartyl-[protein]	-	?
L-leucyl-tRNALeu + N-terminal L-glutamyl-[protein]	Vibrio vulnificus	-	tRNALeu + N-terminal L-leucyl-L-glutamyl-[protein]	-	?

Organism

Organism	UniProt	Comment	Textmining
Vibrio vulnificus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Vibrio vulnificus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-leucyl-tRNALeu + N-terminal L-aspartyl-[protein]	-	Vibrio vulnificus	tRNALeu + N-terminal L-leucyl-L-aspartyl-[protein]	-	?
L-leucyl-tRNALeu + N-terminal L-glutamyl-[protein]	-	Vibrio vulnificus	tRNALeu + N-terminal L-leucyl-L-glutamyl-[protein]	-	?

Synonyms

Synonyms	Comment	Organism
bacterial protein transferase	-	Vibrio vulnificus
BPT	-	Vibrio vulnificus
LD,E-transferase	-	Vibrio vulnificus
Leu-conjugating aa-transferase	-	Vibrio vulnificus

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Release 2023.1 (January 2023)