BRENDA - Enzyme Database
show all sequences of 2.3.1.62

The suitability of different acyl acceptors as substrates for the acyl-CoA: 2-acyl-sn-glycero-3-phosphorylcholine acyltransferase in rat liver microsomes

Holub, B.; Biochim. Biophys. Acta 664, 221-228 (1981)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
palmitoyl-CoA
above 0.064 mM
Rattus norvegicus
stearoyl-CoA
above 0.064 mM
Rattus norvegicus
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
microsome
-
Rattus norvegicus
-
-
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
Rattus norvegicus
reaction in phosphatidylcholine metabolism
CoA + phosphatidylcholine
-
Rattus norvegicus
?
acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
Rattus norvegicus male Wistar
reaction in phosphatidylcholine metabolism
CoA + phosphatidylcholine
-
Rattus norvegicus male Wistar
?
Organism
Organism
UniProt
Commentary
Textmining
Rattus norvegicus
-
male Wistar strain
-
Rattus norvegicus male Wistar
-
male Wistar strain
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
liver
-
Rattus norvegicus
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + phosphatidylcholine
-
487350
Rattus norvegicus
?
acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
reaction in phosphatidylcholine metabolism
487350
Rattus norvegicus
CoA + phosphatidylcholine
-
487350
Rattus norvegicus
?
acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus male Wistar
CoA + phosphatidylcholine
-
487350
Rattus norvegicus male Wistar
?
acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
reaction in phosphatidylcholine metabolism
487350
Rattus norvegicus male Wistar
CoA + phosphatidylcholine
-
487350
Rattus norvegicus male Wistar
?
oleoyl-CoA + 2-palmitoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1-oleoyl-2-palmitoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
palmitoyl-CoA + 2-arachidonoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
palmitoyl-CoA + 2-linolenoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1-palmitoyl-2-linolenoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
palmitoyl-CoA + 2-linoleoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
palmitoyl-CoA + 2-oleoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
palmitoyl-CoA + 2-oleoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus male Wistar
CoA + 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus male Wistar
?
palmitoyl-CoA + 2-palmitoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1,2-dipalmitoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
palmitoyl-CoA + 2-palmitoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus male Wistar
CoA + 1,2-dipalmitoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus male Wistar
?
palmitoyl-CoA + 2-stearoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1-palmitoyl-2-stearoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
palmitoyl-CoA + 2-stearoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus male Wistar
CoA + 1-palmitoyl-2-stearoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus male Wistar
?
stearoyl-CoA + 2-arachidonoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
stearoyl-CoA + 2-linolenoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1-stearoyl-2-linolenoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
stearoyl-CoA + 2-linoleoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1-stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
stearoyl-CoA + 2-oleoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
stearoyl-CoA + 2-palmitoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1-stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
stearoyl-CoA + 2-stearoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1,2-distearoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
Synonyms
Synonyms
Commentary
Organism
acyltransferase
-
Rattus norvegicus
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
palmitoyl-CoA
above 0.064 mM
Rattus norvegicus
stearoyl-CoA
above 0.064 mM
Rattus norvegicus
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
microsome
-
Rattus norvegicus
-
-
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
Rattus norvegicus
reaction in phosphatidylcholine metabolism
CoA + phosphatidylcholine
-
Rattus norvegicus
?
acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
Rattus norvegicus male Wistar
reaction in phosphatidylcholine metabolism
CoA + phosphatidylcholine
-
Rattus norvegicus male Wistar
?
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
liver
-
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + phosphatidylcholine
-
487350
Rattus norvegicus
?
acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
reaction in phosphatidylcholine metabolism
487350
Rattus norvegicus
CoA + phosphatidylcholine
-
487350
Rattus norvegicus
?
acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus male Wistar
CoA + phosphatidylcholine
-
487350
Rattus norvegicus male Wistar
?
acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
reaction in phosphatidylcholine metabolism
487350
Rattus norvegicus male Wistar
CoA + phosphatidylcholine
-
487350
Rattus norvegicus male Wistar
?
oleoyl-CoA + 2-palmitoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1-oleoyl-2-palmitoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
palmitoyl-CoA + 2-arachidonoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
palmitoyl-CoA + 2-linolenoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1-palmitoyl-2-linolenoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
palmitoyl-CoA + 2-linoleoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
palmitoyl-CoA + 2-oleoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
palmitoyl-CoA + 2-oleoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus male Wistar
CoA + 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus male Wistar
?
palmitoyl-CoA + 2-palmitoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1,2-dipalmitoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
palmitoyl-CoA + 2-palmitoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus male Wistar
CoA + 1,2-dipalmitoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus male Wistar
?
palmitoyl-CoA + 2-stearoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1-palmitoyl-2-stearoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
palmitoyl-CoA + 2-stearoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus male Wistar
CoA + 1-palmitoyl-2-stearoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus male Wistar
?
stearoyl-CoA + 2-arachidonoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
stearoyl-CoA + 2-linolenoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1-stearoyl-2-linolenoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
stearoyl-CoA + 2-linoleoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1-stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
stearoyl-CoA + 2-oleoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
stearoyl-CoA + 2-palmitoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1-stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
stearoyl-CoA + 2-stearoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
CoA + 1,2-distearoyl-sn-glycero-3-phosphocholine
-
487350
Rattus norvegicus
?
Other publictions for EC 2.3.1.62
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
756094
Kawana
An accurate and versatile met ...
Mus musculus, Homo sapiens
Biochim. Biophys. Acta
1864
1053-1060
2019
-
-
3
-
-
-
-
-
3
-
-
4
-
3
-
-
-
-
-
3
-
-
12
-
19
3
-
-
-
3
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
3
-
-
4
-
-
-
-
-
3
-
-
12
-
3
-
-
-
3
-
-
-
-
-
-
-
-
-
487355
Arthur
Acylation of 2-acyl-glyceropho ...
Cavia porcellus
Biochem. J.
261
575-580
1989
-
-
-
-
-
-
4
-
1
2
-
1
-
1
-
-
-
-
-
1
-
-
12
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
1
2
-
1
-
-
-
-
-
1
-
-
12
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
487352
Yoshioka
Mechanism for adaptive modific ...
Tetrahymena pyriformis, Tetrahymena pyriformis NT-1
Biochim. Biophys. Acta
793
34-41
1984
-
-
-
-
-
-
-
-
1
-
-
2
-
4
-
-
-
-
-
-
1
-
14
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
1
-
14
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
487350
Holub
The suitability of different a ...
Rattus norvegicus, Rattus norvegicus male Wistar
Biochim. Biophys. Acta
664
221-228
1981
-
-
-
-
-
-
2
-
1
-
-
2
-
6
-
-
-
-
-
1
-
-
20
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
2
-
-
-
-
-
1
-
-
20
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486375
Yamada
Acyltransferase systems involv ...
Saccharomyces cerevisiae, Saccharomyces cerevisiae OC-2
Arch. Biochem. Biophys.
183
281-289
1977
-
-
-
-
-
-
-
-
1
-
-
1
-
3
-
-
-
-
-
-
-
1
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
1
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
487354
Van den Bosch
The acylation of isomeric mono ...
Rattus norvegicus
Biochim. Biophys. Acta
152
694-703
1968
-
-
-
-
-
-
-
-
1
-
-
1
-
1
-
-
-
-
-
1
-
-
2
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486618
Lands
Metabolism of glycerolipids. V ...
Bos taurus, Cavia porcellus, Rattus norvegicus, Sus scrofa
J. Biol. Chem.
240
1905-1911
1965
1
-
-
-
-
-
5
-
4
-
-
4
-
4
-
-
-
-
-
6
-
-
28
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
5
-
-
4
-
-
4
-
-
-
-
-
6
-
-
28
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-