Cloned (Comment) | Organism |
---|---|
cDNAs encoding splicing variants cChAT and pChAT, purified from the rat striatum and pterygopalatine ganglion, respectively, expression analysis. Recombinant expression in HEK-293 cells | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + choline | Rattus norvegicus | - |
CoA + O-acetylcholine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
two splicing variants, peripheral-type pChAT and common-type cChAT | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | cChAT and pChAt expression analysis in brain, overview | Rattus norvegicus | - |
additional information | after axotomy pChAT immunoreactivity is apparent in some brainstem nuclei, such as the dorsal motor nucleus of the vagus nerve, the nucleus ambiguus, and the hypoglossal nucleus, but not in the brainstem neurons of normal rats | Rattus norvegicus | - |
vagus nerve | dorsal motor nucleus of the vagus nerve, contains a peripheral-type pChAT, a splice variant that lacks exons 6-9 of the common-type ChAT, cChAT | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + choline | - |
Rattus norvegicus | CoA + O-acetylcholine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ChAT | - |
Rattus norvegicus |
choline acetyltransferase | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
acetyl-CoA | - |
Rattus norvegicus |
Organism | Comment | Expression |
---|---|---|
Rattus norvegicus | pChAT expression is induced by neuronal damage | up |