Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Hg2+ | noncompetitive with respect to choline, IC50: 0.0004 mM, mixed type inhibition with respect to acetyl-CoA, IC50: 0.0025 mM, activity can be recovered using 2,3-dimercapto-propanol | Electrophorus electricus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + choline | Electrophorus electricus | synthesis of the neurotransmitter acetylcholine | acetylcholine + CoA | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Electrophorus electricus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
electric organ | - |
Electrophorus electricus | - |
electrocyte | - |
Electrophorus electricus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + choline | - |
Electrophorus electricus | acetylcholine + CoA | - |
r | |
acetyl-CoA + choline | synthesis of the neurotransmitter acetylcholine | Electrophorus electricus | acetylcholine + CoA | - |
r |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0005 | - |
Hg2+ | pH 7.4, 37°C | Electrophorus electricus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0025 | - |
noncompetitive with respect to choline, IC50: 0.0004 mM, mixed type inhibition with respect to acetyl-CoA, IC50: 0.0025 mM, activity can be recovered using 2,3-dimercapto-propanol | Electrophorus electricus | Hg2+ |