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Literature summary for 2.3.1.299 extracted from

  • Kim, H.J.; Qiao, Q.; Toop, H.D.; Morris, J.C.; Don, A.S.
    A fluorescent assay for ceramide synthase activity (2012), J. Lipid Res., 53, 1701-1707 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.299

Inhibitors

Inhibitors Comment Organism Structure
FTY720 competitive inhibitor Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Homo sapiens 5783
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ 2 mM used in assay conditions Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
stearoyl-CoA + NBD-labelled sphinganine Homo sapiens NBD-labelled sphinganine is (2S,3R)-2-amino-18-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)octadecane-1,3-diol N-(stearoyl)-sphinganine + CoA
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain highest expression Homo sapiens
-
HEK-293 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
stearoyl-CoA + NBD-labelled sphinganine NBD-labelled sphinganine is (2S,3R)-2-amino-18-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)octadecane-1,3-diol Homo sapiens N-(stearoyl)-sphinganine + CoA
-
 ?

Synonyms

Synonyms Comment Organism
CerS1
-
 Homo sapiens
LASS1
-
 Homo sapiens