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Literature summary for 2.3.1.291 extracted from
- Linking the ceramide synthases (CerSs) 4 and 5 with apoptosis, endometrial and colon cancers (2015), Exp. Mol. Pathol., 98, 585-592 .
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | both isoforms CerS4 and CerS5 are up-regulated in endometrial and colon cancer cells. Apoptosis induction by anastrozole or 5-FU results in down-regulation of CerS4 and CerS5 in endometrial and colon cancer cells | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q8N5B7 | isoform CerS5 | - |
| Homo sapiens | Q9HA82 | isoform CerS4 | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| Caco-2 cell | - |
Homo sapiens | - |
| HEC-1-A cell | - |
Homo sapiens | - |
| HT-29 cell | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CerS4 | - |
Homo sapiens |
| CerS5 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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