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Literature summary for 2.3.1.28 extracted from

  • Zaidenzaig, Y.; Fitton, J.E.; Packman, L.C.; Shaw, W.V.
    Characterization and comparison of chloramphenicol acetyltransferase variants (1979), Eur. J. Biochem., 100, 609-618.
    View publication on PubMed
Search for more literature for 2.3.1.28

Inhibitors

Inhibitors Comment Organism Structure
2,2'-dithiobis(pyridine)
-
 Clostridium perfringens
2,2'-dithiobis(pyridine)
-
 Haemophilus influenzae
2,2'-dithiobis(pyridine)
-
 Proteus mirabilis
2,2'-dithiobis(pyridine)
-
 Streptococcus agalactiae
2,2'-dithiobis(pyridine)
-
 Streptomyces acrimycini

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0093
-
 chloramphenicol
-
 Streptococcus agalactiae
0.01
-
 chloramphenicol
-
 Streptococcus pneumoniae
0.0166
-
 chloramphenicol
-
 Streptomyces acrimycini
0.0175
-
 chloramphenicol
-
 Haemophilus parainfluenzae
0.0205
-
 chloramphenicol
-
 Agrobacterium tumefaciens
0.0215
-
 chloramphenicol
-
 Clostridium perfringens
0.031
-
 chloramphenicol
-
 Proteus mirabilis

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
22500
-
 x * 22500, SDS-PAGE Streptococcus pneumoniae
22500
-
 x * 22500, SDS-PAGE Proteus mirabilis
22500
-
 x * 22500, SDS-PAGE Staphylococcus sp.
22500
-
 x * 22500, SDS-PAGE Clostridium perfringens
22500
-
 x * 22500, SDS-PAGE Streptococcus agalactiae
22500
-
 x * 22500, SDS-PAGE Haemophilus parainfluenzae

Organism

Organism UniProt Comment Textmining
Agrobacterium tumefaciens
-
-
-
Clostridium perfringens
-
-
-
Haemophilus influenzae
-
-
-
Haemophilus parainfluenzae
-
-
-
Proteus mirabilis
-
-
-
Staphylococcus sp.
-
 type A, type B and type C
-
Streptococcus agalactiae
-
-
-
Streptococcus pneumoniae
-
-
-
Streptomyces acrimycini
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + chloramphenicol
-
 Haemophilus influenzae CoA + chloramphenicol 3-acetate
-
 ?
acetyl-CoA + chloramphenicol
-
 Proteus mirabilis CoA + chloramphenicol 3-acetate
-
 ?
acetyl-CoA + chloramphenicol
-
 Staphylococcus sp. CoA + chloramphenicol 3-acetate
-
 ?
acetyl-CoA + chloramphenicol
-
 Agrobacterium tumefaciens CoA + chloramphenicol 3-acetate
-
 ?
acetyl-CoA + chloramphenicol
-
 Clostridium perfringens CoA + chloramphenicol 3-acetate
-
 ?
acetyl-CoA + chloramphenicol
-
 Streptococcus agalactiae CoA + chloramphenicol 3-acetate
-
 ?
acetyl-CoA + chloramphenicol
-
 Streptococcus pneumoniae CoA + chloramphenicol 3-acetate
-
 ?
acetyl-CoA + chloramphenicol
-
 Haemophilus parainfluenzae CoA + chloramphenicol 3-acetate
-
 ?
acetyl-CoA + chloramphenicol
-
 Streptomyces acrimycini CoA + chloramphenicol 3-acetate
-
 ?

Subunits

Subunits Comment Organism
?
-
 Agrobacterium tumefaciens
?
-
 Haemophilus influenzae
?
-
 Streptomyces acrimycini
? x * 22500, SDS-PAGE Streptococcus pneumoniae
? x * 22500, SDS-PAGE Staphylococcus sp.
? x * 22500, SDS-PAGE Proteus mirabilis
? x * 22500, SDS-PAGE Haemophilus parainfluenzae
? x * 22500, SDS-PAGE Streptococcus agalactiae
? x * 22500, SDS-PAGE Clostridium perfringens