Application | Comment | Organism |
---|---|---|
medicine | triple-negative breast cancer cells resistant to glutaminase inhibitor CB-839 have increased CPT2 protein and CPT1 activity levels. CB-839-resistant triple-negative breast cancer cells mobilize more fatty acids into mitochondria for oxidation | Homo sapiens |
medicine | triple-negative breast cancer cells resistant to glutaminase inhibitor CB-839 have increased CPT2 protein and CPT1 activity levels. CB-839-resistant triple-negative breast cancer cells mobilize more fatty acids into mitochondria for oxidation. Inhibition of both glutaminase and CPT1 decreases cell proliferation and migration of CB-839-resistant cells compared with single inhibition of each enzyme | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Homo sapiens | P23786 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
breast cancer cell | - |
Homo sapiens | - |
BT-549 cell | - |
Homo sapiens | - |
HCC-1937 cell | - |
Homo sapiens | - |
HCC-70 cell | - |
Homo sapiens | - |
MDA-MB-157 cell | - |
Homo sapiens | - |
MDA-MB-453 cell | - |
Homo sapiens | - |
MDA-MB-468 cell | - |
Homo sapiens | - |