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Literature summary for 2.3.1.21 extracted from

  • Wang, C.C.; Si, L.F.; Li, W.Y.; Zheng, J.L.
    A functional gene encoding carnitine palmitoyltransferase 1 and its transcriptional and kinetic regulation during fasting in large yellow croaker (2019), Comp. Biochem. Physiol. B, 231, 26-33 .
    View publication on PubMed
Search for more literature for 2.3.1.21

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.38
-
 L-carnitine 25°C, pH not specified in the publication Larimichthys crocea

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Larimichthys crocea 5739
-

Organism

Organism UniProt Comment Textmining
Larimichthys crocea A0A0F8C7P8 isoform CPT1a
-

Source Tissue

Source Tissue Comment Organism Textmining
liver highest mRNA expression level Larimichthys crocea
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
palmitoyl-CoA + L-carnitine
-
 Larimichthys crocea CoA + L-palmitoylcarnitine
-
 ?

Expression

Organism Comment Expression
Larimichthys crocea Cpt1A mRNA expression dramatically increases and activity remains unchanged after fasting up

General Information

General Information Comment Organism
physiological function fasting does not significantly change Vmax and free carnitine content in liver. Catalytic efficiency (Vmax/Km) and the ratio free carnitine/Km increases in fish fasted for 4 days. Both indicators decline when fish fast for 12 days Larimichthys crocea