Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.1.122 extracted from

  • Huc, E.; de Sousa-DAuria, C.; de la Sierra-Gallay, I.L.; Salmeron, C.; van Tilbeurgh, H.; Bayan, N.; Houssin, C.; Daffe, M.; Tropis, M.
    Identification of a mycoloyl transferase selectively involved in O-acylation of polypeptides in Corynebacteriales (2013), J. Bacteriol., 195, 4121-4128.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.122

Cloned(Commentary)

Cloned (Comment) Organism
-
 Corynebacterium glutamicum

Crystallization (Commentary)

Crystallization (Comment) Organism
native protein, to 1.75 A resolution. Strucutre shows the presence of a unique loop that is absent from enzymes that transfer mycoloyl residues onto both trehalose and the cell wall arabinogalactan Corynebacterium glutamicum

Protein Variants

Protein Variants Comment Organism
S189V mutation in putative catalytic serine, complete loss of mycoloyltransferase activity Corynebacterium glutamicum

Organism

Organism UniProt Comment Textmining
Corynebacterium glutamicum Q8NTG4
-
-
Corynebacterium glutamicum DSM 20300 Q8NTG4
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha,alpha-trehalose 6,6'-dimycolate + PorA O-acylation of pore-forming protein Corynebacterium glutamicum alpha,alpha-trehalose 6-monomycolate + mycoloyl-PorA
-
 ?
alpha,alpha-trehalose 6,6'-dimycolate + PorA O-acylation of pore-forming protein Corynebacterium glutamicum DSM 20300 alpha,alpha-trehalose 6-monomycolate + mycoloyl-PorA
-
 ?
alpha,alpha-trehalose 6,6'-dimycolate + PorH O-acylation of pore-forming protein Corynebacterium glutamicum alpha,alpha-trehalose 6-monomycolate + mycoloyl-PorH
-
 ?
alpha,alpha-trehalose 6,6'-dimycolate + PorH O-acylation of pore-forming protein Corynebacterium glutamicum DSM 20300 alpha,alpha-trehalose 6-monomycolate + mycoloyl-PorH
-
 ?
additional information enzyme additionally catalyzes the transfer of the fatty acid residue to yield O-acylated polypeptides Corynebacterium glutamicum ?
-
 ?
additional information enzyme additionally catalyzes the transfer of the fatty acid residue to yield O-acylated polypeptides Corynebacterium glutamicum DSM 20300 ?
-
 ?

Synonyms

Synonyms Comment Organism
cg0413
-
 Corynebacterium glutamicum
CMT1
-
 Corynebacterium glutamicum
corynomycoloyl transferase C
-
 Corynebacterium glutamicum
MytC
-
 Corynebacterium glutamicum

General Information

General Information Comment Organism
physiological function inactivation of corynomycoloyl transferase C specifically abolishes the O-modification of the pore-forming proteins PorA and PorH, which is critical for their biological activity Corynebacterium glutamicum