Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Saccharopolyspora erythraea |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + erythromycin C | Saccharopolyspora erythraea | - |
S-adenosyl-L-homocysteine + erythromycin A | - |
? | |
S-adenosyl-L-methionine + erythromycin D | Saccharopolyspora erythraea | - |
S-adenosyl-L-homocysteine + erythromycin B | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharopolyspora erythraea | A4F7P5 | - |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
S-adenosyl-L-methionine + erythromycin C = S-adenosyl-L-homocysteine + erythromycin A | (1) | Saccharopolyspora erythraea |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + erythromycin C | - |
Saccharopolyspora erythraea | S-adenosyl-L-homocysteine + erythromycin A | - |
? | |
S-adenosyl-L-methionine + erythromycin D | - |
Saccharopolyspora erythraea | S-adenosyl-L-homocysteine + erythromycin B | - |
? |
Synonyms | Comment | Organism |
---|---|---|
EryG | - |
Saccharopolyspora erythraea |
General Information | Comment | Organism |
---|---|---|
malfunction | eryG mutant strain lacks detectable erythromycin O-methyltransferase activity with erythromycin C, erythromycin D, or the analogs 2-norerythromycin C and 2-norerythromycin D as substrates | Saccharopolyspora erythraea |
physiological function | the enzyme catalyzes all of the 3''-O-methylation reactions of the erythromycin biosynthetic pathway in Saccharopolyspora erythraea | Saccharopolyspora erythraea |