show all | hide all No of entries

Information on EC - erythromycin 3''-O-methyltransferase

for references in articles please use BRENDA:EC2.1.1.254
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
       erythromycin 3''-O-methyltransferase
IUBMB Comments
The enzyme methylates the 3 position of the mycarosyl moiety of erythromycin C, forming the most active form of the antibiotic, erythromycin A. It can also methylate the precursor erythromycin D, forming erythromycin B, which is then converted to erythromycin A by EC, erythromycin 12 hydroxylase.
Specify your search results
Select one or more organisms in this record: ?
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
EryG, more
S-adenosyl-L-methionine + erythromycin C = S-adenosyl-L-homocysteine + erythromycin A
show the reaction diagram
Saccharopolyspora erythraea
S-adenosyl-L-methionine + erythromycin D = S-adenosyl-L-homocysteine + erythromycin B
show the reaction diagram
Select items on the left to see more content.