Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.6.5.5 extracted from

  • Mueller, J.; Heller, M.; Uldry, A.C.; Braga, S.; Mueller, N.
    Nitroreductase activites in Giardia lamblia ORF 17150 encodes a quinone reductase with nitroreductase activity (2021), Pathogens, 10, 129 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.6.5.5

Organism

Organism UniProt Comment Textmining
Giardia intestinalis A8BSH8
-
-
Giardia intestinalis ATCC 50803 A8BSH8
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
menadione + NADPH + H+
-
 Giardia intestinalis menadiol + NADP+
-
 ?
menadione + NADPH + H+
-
 Giardia intestinalis ATCC 50803 menadiol + NADP+
-
 ?
additional information coenzyme Q and tetracycline may be used as electron acceptors, but with much lower specific activities than menadione. Nitro compounds dinitrotoluene, 7-nitrocoumarin, and metronidazole can be used as electron acceptors Giardia intestinalis ?
-
-
additional information coenzyme Q and tetracycline may be used as electron acceptors, but with much lower specific activities than menadione. Nitro compounds dinitrotoluene, 7-nitrocoumarin, and metronidazole can be used as electron acceptors Giardia intestinalis ATCC 50803 ?
-
-

Synonyms

Synonyms Comment Organism
ORF 17150
-
 Giardia intestinalis

Cofactor

Cofactor Comment Organism Structure
NADPH recombinant enzyme largely prefers NADPH to NADH Giardia intestinalis

General Information

General Information Comment Organism
physiological function enzyme is a flavoprotein with NADPH-dependent quinone reductase and nitroreductase activities Giardia intestinalis