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Literature summary for 1.5.3.5 extracted from

  • Decker, K.; Dai, V.D.; M๖hler, H.; Bruhmuller, M.
    D- and L-6-hydroxynicotine oxidase, enantioenzymes of Arthrobacter oxidans (1972), Z. Naturforsch. B, 27, 1072-1073.
    View publication on PubMed
Search for more literature for 1.5.3.5

Inhibitors

Inhibitors Comment Organism Structure
6-hydroxy-D-nicotine competitive inhibitor Paenarthrobacter nicotinovorans
methylene blue strong inhibitor Paenarthrobacter nicotinovorans

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.000082
-
 FAD
-
 Paenarthrobacter nicotinovorans
0.02
-
 6-hydroxy-L-nicotine
-
 Paenarthrobacter nicotinovorans

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
93000
-
 sedimentation equilibrium Paenarthrobacter nicotinovorans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-6-hydroxynicotine + H2O + O2 Paenarthrobacter nicotinovorans
-
 1-(6-hydroxypyrid-3-yl)-4-(methylamino)-butan-1-one + H2O2
-
 ?

Organism

Organism UniProt Comment Textmining
Paenarthrobacter nicotinovorans
-
 formerly Arthrobacter oxidans
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-6-hydroxynicotine + H2O + O2
-
 Paenarthrobacter nicotinovorans 1-(6-hydroxypyrid-3-yl)-4-(methylamino)-butan-1-one + H2O2
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
29.3
-
 6-hydroxy-L-nicotine
-
 Paenarthrobacter nicotinovorans

Cofactor

Cofactor Comment Organism Structure
FAD 1 FAD per subunit, non-covalently bound Paenarthrobacter nicotinovorans