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Literature summary for 1.21.1.1 extracted from

  • McTamney, P.M.; Rokita, S.E.
    A mammalian reductive deiodinase has broad power to dehalogenate chlorinated and brominated substrates (2009), J. Am. Chem. Soc., 131, 14212-14213.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-bromo-L-tyrosine + NADPH + H+
-
 Homo sapiens L-tyrosine + NADP+ + Br-
-
 ?
3-chloro-L-tyrosine + NADPH + H+
-
 Homo sapiens L-tyrosine + NADP+ + Cl-
-
 ?
3-iodo-L-tyrosine + NADPH + H+
-
 Homo sapiens L-tyrosine + NADP+ + I-
-
 ?

Synonyms

Synonyms Comment Organism
IYD
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
flavin presence of a neutral flavin radical during the reaction. Radical is stable and persists at 4°C under aerobic conditions for many days Homo sapiens