Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-aminopentanoate | - |
Rattus norvegicus | |
AMP | - |
Rattus norvegicus | |
L-hydroxyproline | - |
Rattus norvegicus | |
p-hydroxymercuribenzoate | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Rattus norvegicus | |
0.09 | - |
1-pyrroline-5-carboxylate | - |
Rattus norvegicus | |
0.17 | - |
1-pyrroline-5-carboxylate | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | matrix | Homo sapiens | 5739 | - |
mitochondrion | matrix | Rattus norvegicus | 5739 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
59000 | - |
2 * 59000, SDS-PAGE | Rattus norvegicus |
66000 | - |
66000, SDS-PAGE | Homo sapiens |
115000 | - |
sucrose-glycerol density gradient sedimentation | Rattus norvegicus |
142000 | - |
gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
27.1 | - |
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-pyrroline-5-carboxylate + NAD+ + H2O | - |
Homo sapiens | L-glutamate + NADH | - |
ir | |
1-pyrroline-5-carboxylate + NAD+ + H2O | - |
Rattus norvegicus | L-glutamate + NADH | - |
ir | |
additional information | slight activity with glutaric semialdehyde and adipic semialdehyde | Homo sapiens | ? | - |
? | |
additional information | slight activity with glutaric semialdehyde and adipic semialdehyde | Rattus norvegicus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 59000, SDS-PAGE | Rattus norvegicus |
dimer | 66000, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
P5C dehydrogenase | - |
Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | 8.5 | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Homo sapiens | |
NAD+ | - |
Rattus norvegicus |