Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.19.30 extracted from

  • Kaewsuwan, S.; Cahoon, E.B.; Perroud, P.F.; Wiwat, C.; Panvisavas, N.; Quatrano, R.S.; Cove, D.J.; Bunyapraphatsara, N.
    Identification and functional characterization of the moss Physcomitrella patens DELTA5-desaturase gene involved in arachidonic and eicosapentaenoic acid biosynthesis (2006), J. Biol. Chem., 281, 21988-21997.
    View publication on PubMed
Search for more literature for 1.14.19.30

Cloned(Commentary)

Cloned (Comment) Organism
expression of the enzyme in Saccharomyces cerevisiae results in the production of the DELTA5-containing fatty acid arachidonic acid in cells that are provided di-homo-gamma-linolenic acid Physcomitrium patens

Organism

Organism UniProt Comment Textmining
Physcomitrium patens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
an (8Z,11Z,14Z)-icosa-8,11,14-trienoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+ (8Z,11Z,14Z)-icosa-8,11,14-trienoate i.e. di-homo-gamma-linolenate. Expression of the enzyme in Saccharomyces cerevisiae results in the production of the DELTA5-containing fatty acid arachidonic acid in cells that are provided di-homo-gamma-linolenic acid Physcomitrium patens a (5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-tetraenoyl-[glycerolipid] + ferricytochrome b5 + 2 H2O (5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-tetraenoate i.e. arachidonate ?
an (8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+
-
 Physcomitrium patens a (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoyl-[glycerolipid] + ferricytochrome b5 + 2 H2O
-
 ?
additional information no products are detected with the C18 fatty acid linoleic and gamma-linolenic acids or with the C22 fatty acid adrenic and docosapentaenoic acids Physcomitrium patens ?
-
 ?

Synonyms

Synonyms Comment Organism
DELTA5-desaturase
-
 Physcomitrium patens
PPDES5
-
 Physcomitrium patens