Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | no significant changes in HO-1 mRNA levels between ethanol treated and pair-fed control | Rattus norvegicus |
Application | Comment | Organism |
---|---|---|
medicine | chronic ethanol feeding induces 5-aminolevulinic acid synthase-1 (ALAS1) mRNA, cytosolic ALAS1 and mature ALAS1 protein levels, but not those of HO-1 in rat livers, which provides novel insights into the effects of chronic ethanol consumption on hepatic heme biosynthesis and porphyrias | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male sprague-dawley rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
forebrain | HO-1 mRNA levels are 66% of those in liver | Rattus norvegicus | - |
liver | - |
Rattus norvegicus | - |
additional information | expression of HO-1 is tissue-specific, and there is a correspondence between levels of HO-1 mRNA and protein | Rattus norvegicus | - |
skeletal muscle | is slightly detectable in the abdominal skeletal muscle | Rattus norvegicus | - |
spleen | highest expression of HO-1 mRNA levels in the spleen, 6.6fold of those in the liver | Rattus norvegicus | - |
Synonyms | Comment | Organism |
---|---|---|
heme oxygenase-1 | - |
Rattus norvegicus |
HO-1 | - |
Rattus norvegicus |