Cloned (Comment) | Organism |
---|---|
expression of wild-type heme oxygenase-1 and 2 and heme oxygenase-2 C264A/C281A double mutant in Escherichia coli | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-morpholinosydnonimine | NO-donor, 27% inhibition of recombinant heme oxygenase-2 | Rattus norvegicus | |
S-nitroso-N-acetyl-pennicillamine | NO-donor, 23% inhibition of recombinant heme oxygenase-2 | Rattus norvegicus | |
sodium nitroprusside | NO-donor, 58% inhibition of recombinant heme oxygenase-2 | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
heme | hemoprotein, heme is both substrate and cofactor, heme oxygenase-2 binds heme at heme regulatory motifs with a conserved Cys-Pro pair | Rattus norvegicus |