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Literature summary for 1.14.14.178 extracted from

  • Yoshimitsu, Y.; Tanaka, K.; Fukuda, W.; Asami, T.; Yoshida, S.; Hayashi, K.; Kamiya, Y.; Jikumaru, Y.; Shigeta, T.; Nakamura, Y.; Matsuo, T.; Okamoto, S.
    Transcription of DWARF4 plays a crucial role in auxin-regulated root elongation in addition to brassinosteroid homeostasis in Arabidopsis thaliana (2011), PLoS ONE, 6, e23851.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
gene DWF4, semi-quantitative reverse-transcriptase PCR expression analysis Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information construction of DWF4::GUS plants, enzyme expression patterns in response to brassinazole and brassinolide in roots, overview Arabidopsis thaliana

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana O64989 gene DWARF4 or DWF4
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Source Tissue

Source Tissue Comment Organism Textmining
root both primary and lateral roots Arabidopsis thaliana
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Synonyms

Synonyms Comment Organism
C-22 hydroxylase
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 Arabidopsis thaliana

Expression

Organism Comment Expression
Arabidopsis thaliana downregulation of enzyme expression by brassinosteroid biosynthesis inhibitor brassinazole down
Arabidopsis thaliana upreguation by bioactive brassinosteroid, brassinolide up

General Information

General Information Comment Organism
metabolism the expression of DWARF4, which encodes a C-22 hydroxylase, is crucial for brassinosteroid biosynthesis and for the feedback control of endogenous brassinosteroid levels. The amount of the DWF4 mRNA precursor either decreases or increases, similarly with its mature form, in response to an exogenously applied bioactive brassinosteroid, brassinolide, and a brassinosteroid biosynthesis inhibitor, brassinazole, respectively. Brassinosteroids act positively on root elongation under the control of auxin Arabidopsis thaliana
physiological function the expression of DWARF4, which encodes a C-22 hydroxylase, is crucial for brassinosteroid biosynthesis and for the feedback control of endogenous brassinosteroid levels. DWF4 transcription plays an important role in the brassinosteroid-auxin crosstalk associated with root elongation, in addition to its role in brassinosteroid homeostasis Arabidopsis thaliana