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Literature summary for 1.14.14.154 extracted from
- The cytochrome P450 lanosterol 14alpha-demethylase gene is a demethylation inhibitor fungicide resistance determinant in Monilinia fructicola field isolates from Georgia (2008), Appl. Environ. Microbiol., 74, 359-366.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | effects of demethylation inhibitor fungicides on enzyme gene expression, resistamce occurs, but some are inductive, overview | Monilinia fructicola |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene CYP51, DNA and amino acid sequence determination and analysis, gene copy numbers and silent nucleotide variations in the coding region of the MfCYP51 gene from different isolates, expression analysis, overview | Monilinia fructicola |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Monilinia fructicola | the enzyme is a demethylation inhibitor fungicide resistance determinant in Monilinia fructicola field isolates | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Monilinia fructicola | A7LM25 | fragment; field isolates from Georgia, which are demethylation inhibitor fungicides-sensitive or demethylation inhibitor fungicides-resistant, gene CYP51 | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| additional information | CYP51 shows constitutive expression | Monilinia fructicola | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the enzyme is a demethylation inhibitor fungicide resistance determinant in Monilinia fructicola field isolates | Monilinia fructicola | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CYP51 | - |
Monilinia fructicola |
| cytochrome P450 lanosterol 14alpha-demethylase | - |
Monilinia fructicola |
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