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Literature summary for 1.14.11.67 extracted from
- The histone H3K4 demethylase JARID1A directly interacts with haematopoietic transcription factor GATA1 in erythroid cells through its second PHD domain (2020), R. Soc. Open Sci., 7, 191048 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | Q3UXZ9 | isoform KDM5A | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| erythrocyte | - |
Mus musculus | - |
| MEL-585 cell | expression of endogenous JARID1A is detected in both undifferentiated MEL cells, and MEL cells undergoing terminal erythroid maturation | Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Jarid1a | - |
Mus musculus |
| KDM5A | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | demethylase KDM5A/JARID1A interacts with the haematopoietic-specific master transcription proteins SCL and GATA1 in red blood cells. A direct physical contact is obeserved between GATA1 and the second PHD domain of JARID1A | Mus musculus |
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Release 2023.1 (January 2023)
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