BRENDA - Enzyme Database show
show all sequences of 1.13.11.58

Computational analysis of tuberization protein linoleate 9S-lipoxygenase 3 from Solanum tuberosum

Rameshwari, R.; Madhu, S.; Prasad, V.; Chapadgaonkar, S.; Int. J. ChemTech Res. 8, 294-310 (2015)
No PubMed abstract available

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
gene LOX1.3, DNA and amino acid sequence determination and analysis, sequence comparisons, phylogenetic analysis
Solanum tuberosum
Engineering
Amino acid exchange
Commentary
Organism
additional information
expression of antisense coding sequence of a specific tuber LOX, the suppression mutant POTLX-1 exhibits a significant reduction in LOX activity in stolons and tubers
Solanum tuberosum
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Fe2+
1 metal ion per subunit
Solanum tuberosum
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
alpha-linolenic acid + O2
Solanum tuberosum
-
(10E,12Z)-9-hydroperoxy-10,12,15-octadecaterieonoic acid
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Solanum tuberosum
Q43189
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
additional information
accumulation of LOX 1 class transcript is restricted to developing tubers, stolons, and roots correlating mRNA accumulation positively with tuber initiation and growth
Solanum tuberosum
-
root
-
Solanum tuberosum
-
tuber
-
Solanum tuberosum
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
alpha-linolenic acid + O2
-
742693
Solanum tuberosum
(10E,12Z)-9-hydroperoxy-10,12,15-octadecaterieonoic acid
-
-
-
?
Subunits
Subunits
Commentary
Organism
More
primary and secondary structure analysis of linoleate 9S-lipoxygenase 3, domain structure, especially the PLAT domain that forms a beta-sandwich composed of two sheets of four strands each, overview
Solanum tuberosum
Cloned(Commentary) (protein specific)
Commentary
Organism
gene LOX1.3, DNA and amino acid sequence determination and analysis, sequence comparisons, phylogenetic analysis
Solanum tuberosum
Engineering (protein specific)
Amino acid exchange
Commentary
Organism
additional information
expression of antisense coding sequence of a specific tuber LOX, the suppression mutant POTLX-1 exhibits a significant reduction in LOX activity in stolons and tubers
Solanum tuberosum
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Fe2+
1 metal ion per subunit
Solanum tuberosum
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
alpha-linolenic acid + O2
Solanum tuberosum
-
(10E,12Z)-9-hydroperoxy-10,12,15-octadecaterieonoic acid
-
-
?
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
additional information
accumulation of LOX 1 class transcript is restricted to developing tubers, stolons, and roots correlating mRNA accumulation positively with tuber initiation and growth
Solanum tuberosum
-
root
-
Solanum tuberosum
-
tuber
-
Solanum tuberosum
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
alpha-linolenic acid + O2
-
742693
Solanum tuberosum
(10E,12Z)-9-hydroperoxy-10,12,15-octadecaterieonoic acid
-
-
-
?
Subunits (protein specific)
Subunits
Commentary
Organism
More
primary and secondary structure analysis of linoleate 9S-lipoxygenase 3, domain structure, especially the PLAT domain that forms a beta-sandwich composed of two sheets of four strands each, overview
Solanum tuberosum
General Information
General Information
Commentary
Organism
evolution
analysis of functional domains, families and motifs along with the phylogenetic analysis
Solanum tuberosum
metabolism
the enzyme takes part in the LOX pathway, overview
Solanum tuberosum
physiological function
the tuberization protein linoleate 9S-lipoxygenase 3 is not the only gene responsible for tuberization in potato. Tuber formation process regulation, overview
Solanum tuberosum
General Information (protein specific)
General Information
Commentary
Organism
evolution
analysis of functional domains, families and motifs along with the phylogenetic analysis
Solanum tuberosum
metabolism
the enzyme takes part in the LOX pathway, overview
Solanum tuberosum
physiological function
the tuberization protein linoleate 9S-lipoxygenase 3 is not the only gene responsible for tuberization in potato. Tuber formation process regulation, overview
Solanum tuberosum
Other publictions for EC 1.13.11.58
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
742051
Roychowdhury
Functional characterization o ...
Oryza sativa, Oryza sativa Japonica Group
BioMed Res. Int.
2016
4275904
2016
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742627
Schiller
A dual positional specific li ...
Malus domestica
Hortic. Res.
2
15003-15015
2015
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3
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742693
Rameshwari
-
Computational analysis of tub ...
Solanum tuberosum
Int. J. ChemTech Res.
8
294-310
2015
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3
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743426
Zhou
The 9-lipoxygenase Osr9-LOX1 ...
Oryza sativa Japonica Group
Physiol. Plant.
152
59-69
2014
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1
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1
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2
2
1
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725160
Li
A chitosan induced 9-lipoxygen ...
Cynanchum gracillimum
Int. J. Mol. Sci.
13
540-551
2012
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1
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725794
Nam
Interactions among LOX metabol ...
Ipomoea nil, Ipomoea nil Choisy
J. Plant Physiol.
169
1815-1820
2012
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726018
Vicente
Role of 9-lipoxygenase and alp ...
Arabidopsis thaliana
Mol. Plant
5
914-928
2012
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3
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724660
Huang
Cloning and characterization o ...
Nicotiana benthamiana
BMC Biotechnol.
11
30
2011
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725855
Hamberg
Efficient and specific convers ...
Beta vulgaris
Lipids
46
873-878
2011
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1
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706336
Hwang
The pepper 9-lipoxygenase gene ...
Capsicum annuum, Capsicum annuum Nockwang
Plant Physiol.
152
948-967
2010
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1
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2
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11
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6
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2
1
2
2
706392
Park
Comparative molecular and bioc ...
Zea mays
Planta
231
1425-1437
2010
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729971
Zheng
Dioxygenase activity of epider ...
Homo sapiens
J. Biol. Chem.
285
39866-39875
2010
1
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1
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702392
Chechetkin
Specificity of oxidation of li ...
Zea mays
Biochemistry
74
855-861
2009
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705464
Boeglin
Investigation of substrate bin ...
Arabidopsis thaliana, Solanum lycopersicum
Lipids
43
979-987
2008
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2
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1
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705465
Andreou
On the substrate binding of li ...
Arabidopsis thaliana, Solanum tuberosum
Lipids
44
207-215
2008
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705472
Bannenberg
Diversity of the enzymatic act ...
Arabidopsis thaliana
Lipids
44
85-95
2008
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705809
Gao
Maize 9-lipoxygenase ZmLOX3 co ...
Zea mays
Mol. Plant Microbe Interact.
21
98-109
2008
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705807
Gao
Disruption of a maize 9-lipoxy ...
Zea mays
Mol. Plant Microbe Interact.
20
922-933
2007
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706206
Vellosillo
Oxylipins produced by the 9-li ...
Arabidopsis thaliana
Plant Cell
19
831-846
2007
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4
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706263
Marmey
The gene is associated with th ...
Gossypium hirsutum
Plant Physiol. Biochem.
45
596-606
2007
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674121
Kuo
Lipoxygenase from banana leaf: ...
Musa acuminata
J. Agric. Food Chem.
54
3151-3156
2006
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674135
Garbe
Dual positional and stereospec ...
Hordeum vulgare
J. Agric. Food Chem.
54
946-955
2006
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-
-
-
705460
Hamberg M.
Isolation and structures of tw ...
Clematis vitalba
Lipids
39
565-569
2004
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
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-
1
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-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
706170
Mizuno
A new 9-lipoxygenase cDNA from ...
Oryza sativa
Plant Cell Physiol.
44
1168-1175
2003
-
1
1
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
2
-
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2
-
1
1
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1
1
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1
1
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-
-
2
-
-
2
-
1
1
-
-
1
1
-
-
-
-
-
-
-
-
703536
Mita
Molecular cloning and biochemi ...
Prunus dulcis, Prunus dulcis Mill.
Eur. J. Biochem.
268
1500-1507
2001
-
-
1
-
-
-
-
-
-
-
1
-
-
2
-
-
1
-
-
1
-
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2
1
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1
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1
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1
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1
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-
-
-
1
-
1
-
-
2
1
-
-
-
-
1
-
-
1
-
-
-
-
-
-
706370
Ben-Hayyim
Preferential induction of a 9- ...
Citrus sinensis
Planta
212
367-375
2001
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
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-
-
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-
-
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-
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
704382
Royo
Characterization of three pota ...
Solanum tuberosum
J. Biol. Chem.
271
21012-21009
1996
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
4
-
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2
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1
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1
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-
4
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
396147
Doderer
Purification and characterizat ...
Hordeum vulgare
Biochim. Biophys. Acta
1120
97-104
1992
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
1
-
-
1
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1
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1
1
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2
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