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Information on EC 1.13.11.58 - linoleate 9S-lipoxygenase

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IUBMB Comments
Contains nonheme iron. A common plant lipoxygenase that oxidizes linoleate and alpha-linolenate, the two most common polyunsaturated fatty acids in plants, by inserting molecular oxygen at the C9 position with (S)-configuration. The enzyme plays a physiological role during the early stages of seedling growth. The enzyme from Arabidopsis thaliana shows comparable activity towards linoleate and linolenate . EC 1.13.11.12 (linoleate 13S-lipoxygenase) catalyses a similar reaction at another position of these fatty acids.
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The enzyme appears in viruses and cellular organisms
Synonyms
9-lipoxygenase, 9-LO, 9-LOX, 9S-lipoxygenase, AtLOX-1, AtLOX-5, AtLOX1, AtLOX5, CaLOX1, eLOX3, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
linoleate + O2 = (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate
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