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Literature summary for 1.13.11.52 extracted from
- Molecular and functional characterization of the indoleamine 2,3-dioxygenase in grass carp (Ctenopharyngodon idella) (2019), Fish Shellfish Immunol., 89, 301-308 .
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| delta-aminolevulinic acid | - |
Ctenopharyngodon idella |  |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli | Ctenopharyngodon idella |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| levo-1-methyl tryptophan | - |
Ctenopharyngodon idella |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 49000 | - |
calculated from sequence | Ctenopharyngodon idella |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-tryptophan + O2 | Ctenopharyngodon idella | - |
N-formyl-L-kynurenine | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Ctenopharyngodon idella | A0A4D5XKZ6 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Ctenopharyngodon idella |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| intestine | - |
Ctenopharyngodon idella | - |
| liver | highest expression in liver and trunk kidney | Ctenopharyngodon idella | - |
| muscle | - |
Ctenopharyngodon idella | - |
| ovary | - |
Ctenopharyngodon idella | - |
| spleen | - |
Ctenopharyngodon idella | - |
| trunk kidney | highest expression in liver and trunk kidney | Ctenopharyngodon idella | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-tryptophan + O2 | - |
Ctenopharyngodon idella | N-formyl-L-kynurenine | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| IDO | - |
Ctenopharyngodon idella |
pI Value
| Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|
| Ctenopharyngodon idella | calculated from sequence | - |
6.2 |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Ctenopharyngodon idella | recombinant transforming growth factor-beta1 of grass carp could up-regulate the expression of indoleamine 2,3-dioxygenase | up |
| Ctenopharyngodon idella | the enzyme is constitutively expressed in various tissues, and its expression can be significantly up-regulated by LPS and poly(I:C) in peripheral blood leukocytes | up |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the enzyme plays multiple roles in the immunity of fish | Ctenopharyngodon idella |
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