Cloned (Comment) | Organism |
---|---|
for sequencing | Cyprinus carpio |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
selenium | - |
Cyprinus carpio |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione + a lipid hydroperoxide | Cyprinus carpio | - |
glutathione disulfide + lipid + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cyprinus carpio | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Cyprinus carpio | - |
cerebellum | - |
Cyprinus carpio | - |
heart | - |
Cyprinus carpio | - |
kidney | - |
Cyprinus carpio | - |
liver | - |
Cyprinus carpio | - |
midbrain | - |
Cyprinus carpio | - |
muscle | - |
Cyprinus carpio | - |
olfactory lobe | - |
Cyprinus carpio | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione + a lipid hydroperoxide | - |
Cyprinus carpio | glutathione disulfide + lipid + H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | - |
Cyprinus carpio |
Synonyms | Comment | Organism |
---|---|---|
GPx4A | - |
Cyprinus carpio |
GPx4B | - |
Cyprinus carpio |
phospholipid hydroperoxide glutathione peroxidase A | - |
Cyprinus carpio |
phospholipid hydroperoxide glutathione peroxidase B | - |
Cyprinus carpio |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
glutathione | - |
Cyprinus carpio |
Organism | Comment | Expression |
---|---|---|
Cyprinus carpio | 10 mg/l Cd2+ down-regulates gpx4b in liver and olfactory lobe tissues | down |
Cyprinus carpio | in the liver of the carp exposed to 7°C temperature drop, the gpx4a gene is down-regulated as early as 1 h after cold shock to 75% | down |
Cyprinus carpio | in liver direct exposure to low temperature increases the transcription of gpx4b by 2.5fold | up |