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Literature summary for 1.1.1.14 extracted from

  • Lanaspa, M.A.; Andres-Hernando, A.; Rivard, C.J.; Dai, Y.; Li, N.; Berl, T.
    ZAC1 is up-regulated by hypertonicity and decreases sorbitol dehydrogenase expression, allowing accumulation of sorbitol in kidney cells (2009), J. Biol. Chem., 284, 19974-19981.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.1.1.14

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Mus musculus
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 C57/B6 mice
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Source Tissue

Source Tissue Comment Organism Textmining
hippocampus
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 Mus musculus
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IMCD-3 cell cell culture derived from the kidney inner medulla Mus musculus
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inner medullary collecting duct
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 Mus musculus
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inner medullary collecting duct
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 Homo sapiens
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kidney papilla, inner medulla, cortex Mus musculus
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kidney papilla, inner medulla, cortex Homo sapiens
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additional information SDH expression analysis, overview Mus musculus
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additional information SDH expression analysis, overview Homo sapiens
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Synonyms

Synonyms Comment Organism
SDH
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 Mus musculus
SDH
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 Homo sapiens
sorbitol dehydrogenase
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 Mus musculus
sorbitol dehydrogenase
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 Homo sapiens

Expression

Organism Comment Expression
Mus musculus zinc-finger protein ZAC1 is up-regulated under hypertonic stress and negatively regulates expression of SDH down
Homo sapiens zinc-finger protein ZAC1 is up-regulated under hypertonic stress and negatively regulates expression of SDH down

General Information

General Information Comment Organism
metabolism the zinc-finger protein ZAC1 is up-regulated under hypertonic stress and negatively regulates expression of SDH, allowing for accumulation of sorbitol as a compatible organic osmolyte Mus musculus
metabolism the zinc-finger protein ZAC1 is up-regulated under hypertonic stress and negatively regulates expression of SDH, allowing for accumulation of sorbitol as a compatible organic osmolyte Homo sapiens