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Literature summary for 1.1.1.14 extracted from
- Polyol dehydrogenase (1962), Biochem. J., 83, 135-144.
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
- |
Ovis aries |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,10-phenanthroline | - |
Ovis aries |  |
| CuSO4 | - |
Ovis aries | |
| cyanide | - |
Ovis aries | |
| cysteine | at alkaline pH | Ovis aries | |
| glutathione | - |
Ovis aries | |
| p-chloromercuribenzoate | - |
Ovis aries | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.18 | - |
D-xylitol | - |
Ovis aries | |
| 0.6 | - |
NAD+ | - |
Ovis aries | |
| 1.1 | - |
D-sorbitol | - |
Ovis aries | |
| 1.8 | - |
D-ribitol | - |
Ovis aries | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 115000 | - |
ultracentrifugal analysis | Ovis aries |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Ovis aries | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Ovis aries |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Ovis aries | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 14.4 | - |
- |
Ovis aries |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-glycero-D-gluco-heptitol + NAD+ | - |
Ovis aries | ? | - |
? | |
| D-ribitol + NAD+ | - |
Ovis aries | ? | - |
? | |
| D-sorbitol + NAD+ | - |
Ovis aries | D-fructose + NADH + H+ | - |
? | |
| D-xylitol + NAD+ | - |
Ovis aries | ? | - |
? | |
| L-arabitol + NAD+ | - |
Ovis aries | ? | - |
? | |
| L-iditol + NAD+ | - |
Ovis aries | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
D-fructose reduction | Ovis aries |
| 10 | - |
sorbitol oxidation | Ovis aries |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Ovis aries | |
| NADH | - |
Ovis aries | |
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Release 2023.1 (January 2023)
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