Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Disease on EC 7.4.2.10 - ABC-type glutathione transporter

Please use the Disease Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Breast Neoplasms
ABC transporter (P-gp/ABCB1, MRP1/ABCC1, BCRP/ABCG2) expression in the developing human CNS.
Celastrol Inhibits the Proliferation and Decreases Drug Resistance of Cisplatin-Resistant Gastric Cancer SGC7901/DDP Cells.
Modulation of the spacer in N,N-bis(alkanol)amine aryl ester heterodimers led to the discovery of a series of highly potent P-glycoprotein-based multidrug resistance (MDR) modulators.
MRP1 but not MDR1 is associated with response to neoadjuvant chemotherapy in breast cancer patients.
Natural products as multidrug resistance modulators in cancer.
Paeonol reverses paclitaxel resistance in human breast cancer cells by regulating the expression of transgelin 2.
Prediction of Therapy Response and Prognosis in Leukemias by Flow Cytometric MDR Assays.
Salvianolic acid A reverses paclitaxel resistance in human breast cancer MCF-7 cells via targeting the expression of transgelin 2 and attenuating PI3 K/Akt pathway.
Selection of resistant acute myeloid leukemia SKM-1 and MOLM-13 cells by vincristine-, mitoxantrone- and lenalidomide-induced upregulation of P-glycoprotein activity and downregulation of CD33 cell surface exposure.
The Optimization Design Of Lactoferrin Loaded HupA Nanoemulsion For Targeted Drug Transport Via Intranasal Route.
Topotecan is a substrate for multidrug resistance associated protein 4.
Colonic Neoplasms
Hypoxia-inducible factor-1? induces multidrug resistance protein in colon cancer.
Colorectal Neoplasms
The role of MRP1 in the multidrug resistance of colorectal cancer.
Gallbladder Neoplasms
miR-145 sensitizes gallbladder cancer to cisplatin by regulating multidrug resistance associated protein 1.
Neoplasms
Celastrol Inhibits the Proliferation and Decreases Drug Resistance of Cisplatin-Resistant Gastric Cancer SGC7901/DDP Cells.
Combined cytogenetic and array-based comparative genomic hybridization analyses of Wilms tumors: amplification and overexpression of the multidrug resistance associated protein 1 gene (MRP1) in a metachronous tumor.
Effects of clotrimazole on transport mediated by multidrug resistance associated protein 1 (MRP1) in human erythrocytes and tumour cells.
MRP1 but not MDR1 is associated with response to neoadjuvant chemotherapy in breast cancer patients.
p53 mutation, but not in vitro predictor genes of therapeutic efficacy of cisplatin, is clinically relevant in comparing partial and complete responder cases of maxillary squamous cell carcinoma.
Topotecan is a substrate for multidrug resistance associated protein 4.
Retinoblastoma
In vitro and In silico studies on inhibitory effects of curcumin on multi drug resistance associated protein (MRP1) in retinoblastoma cells.
Xeroderma Pigmentosum
p53 mutation, but not in vitro predictor genes of therapeutic efficacy of cisplatin, is clinically relevant in comparing partial and complete responder cases of maxillary squamous cell carcinoma.