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IUBMB Comments The enzyme, characterized from the bacterium Rubrivivax benzoatilyticus JA2, requires no cofactors. It acts on L -phenylalanine and L -glutamate with about 60% of the activity with L -tryptophan, and on L -tyrosine, glycine, and L -alanine with about 30% of the activity.
The expected taxonomic range for this enzyme is: Rubrivivax benzoatilyticus
Synonyms l-tryptophan ammonia lyase, more
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WAL
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L-tryptophan = 3-indoleacrylate + NH3
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L-tryptophan ammonia-lyase (3-indoleacrylate-forming)
The enzyme, characterized from the bacterium Rubrivivax benzoatilyticus JA2, requires no cofactors. It acts on L-phenylalanine and L-glutamate with about 60% of the activity with L-tryptophan, and on L-tyrosine, glycine, and L-alanine with about 30% of the activity.
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glycine
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-
Substrates: about 30% of the activity with L-tryptophan Products: -
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L-glutamate
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-
Substrates: about 60% of the activity with L-tryptophan Products: -
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L-phenylalanine
(E)-cinnamate + NH3
L-tryptophan
3-indoleacrylate + ammonia
L-tyrosine
trans-p-hydroxycinnamate + NH3
L-alanine
?
-
Substrates: about 30% of the activity with L-tryptophan Products: -
?
L-alanine
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Substrates: about 30% of the activity with L-tryptophan Products: -
?
L-phenylalanine
(E)-cinnamate + NH3
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Substrates: about 60% of the activity with L-tryptophan Products: -
?
L-phenylalanine
(E)-cinnamate + NH3
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Substrates: about 60% of the activity with L-tryptophan Products: -
?
L-tryptophan
3-indoleacrylate + ammonia
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Substrates: - Products: -
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L-tryptophan
3-indoleacrylate + ammonia
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Substrates: - Products: 3-indoleacrylate i.e. (2E)-3-(1H-indol-3-yl)prop-2-enoate
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L-tryptophan
3-indoleacrylate + ammonia
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Substrates: - Products: -
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L-tryptophan
3-indoleacrylate + ammonia
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Substrates: - Products: 3-indoleacrylate i.e. (2E)-3-(1H-indol-3-yl)prop-2-enoate
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L-tyrosine
trans-p-hydroxycinnamate + NH3
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Substrates: about 30% of the activity with L-tryptophan Products: -
?
L-tyrosine
trans-p-hydroxycinnamate + NH3
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Substrates: about 30% of the activity with L-tryptophan Products: -
?
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L-tryptophan
3-indoleacrylate + ammonia
L-tryptophan
3-indoleacrylate + ammonia
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Substrates: - Products: -
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L-tryptophan
3-indoleacrylate + ammonia
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Substrates: - Products: -
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0.00004
L-tryptophan
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pH and temperature not specified in the publication
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heterotetramer
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Kumavath, R.N.; Ramana ChV.; Sasikala, Ch.; Barh, D.; Kumar, A.P.; Azevedo, V.
Isolation and characterization of L-tryptophan ammonia lyase from Rubrivivax benzoatilyticus strain JA2
Curr. Protein Pept. Sci.
16
775-781
2015
Rubrivivax benzoatilyticus, Rubrivivax benzoatilyticus JA2
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