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Information on EC 4.2.3.55 - (S)-beta-bisabolene synthase

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EC Tree
     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.3 Acting on phosphates
                4.2.3.55 (S)-beta-bisabolene synthase
IUBMB Comments
The synthesis of (S)-beta-macrocarpene from (2E,6E)-farnesyl diphosphate proceeds in two steps. The first step is the cyclization to (S)-beta-bisabolene. The second step is the isomerization to (S)-beta-macrocarpene (cf. EC 5.5.1.17, (S)-beta-macrocarpene synthase). The enzyme requires Mg2+ or Mn2+ for activity.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
bisabolene synthase, Os08g07100, SaBS, TPS11, TPS6, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(2E,6E)-farnesyl diphosphate = (S)-beta-bisabolene + diphosphate
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