Streptomyces viridochromogenes Streptomyces viridochromogenes DSM 40736
D9XD61
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IUBMB Comments The enzyme, found in the bacterium Streptomyces viridochromogenes , is specific for (2E ,6E )-farnesyl diphosphate.
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(2E,6E)-farnesyl diphosphate + H2O = 7-epi-alpha-eudesmol + diphosphate
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(2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, 7-epi-alpha-eudesmol-forming)
The enzyme, found in the bacterium Streptomyces viridochromogenes, is specific for (2E,6E)-farnesyl diphosphate.
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(2E,6E)-farnesyl diphosphate + H2O
7-epi-alpha-eudesmol + diphosphate
(2E,6E)-farnesyl diphosphate + H2O
7-epi-alpha-eudesmol + diphosphate
Substrates: -
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(2E,6E)-farnesyl diphosphate + H2O
7-epi-alpha-eudesmol + diphosphate
Substrates: no activity with geranyl diphosphate and geranylgeranyl diphosphate. 7-epi-alpha-Eudesmol biosynthesis proceeds via reprotonation of the neutral intermediate hedycaryol
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(2E,6E)-farnesyl diphosphate + H2O
7-epi-alpha-eudesmol + diphosphate
Substrates: -
?
(2E,6E)-farnesyl diphosphate + H2O
7-epi-alpha-eudesmol + diphosphate
Substrates: no activity with geranyl diphosphate and geranylgeranyl diphosphate. 7-epi-alpha-Eudesmol biosynthesis proceeds via reprotonation of the neutral intermediate hedycaryol
?
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(2E,6E)-farnesyl diphosphate + H2O
7-epi-alpha-eudesmol + diphosphate
(2E,6E)-farnesyl diphosphate + H2O
7-epi-alpha-eudesmol + diphosphate
Substrates: -
?
(2E,6E)-farnesyl diphosphate + H2O
7-epi-alpha-eudesmol + diphosphate
Substrates: -
?
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UniProt
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UniProt
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Highest Expressing Human Cell Lines
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EAES_STRVT
Streptomyces viridochromogenes (strain DSM 40736 / JCM 4977 / BCRC 1201 / Tue 494)
343
0
39255
Swiss-Prot
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expression in Escherichia coli BL21
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Rabe, P.; Schmitz, T.; Dickschat, J.S.
Mechanistic investigations on six bacterial terpene cyclases
Beilstein J. Org. Chem.
12
1839-1850
2016
Streptomyces viridochromogenes (D9XD61), Streptomyces viridochromogenes DSM 40736 (D9XD61)
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