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Literature summary for 4.2.3.169 extracted from

  • Rabe, P.; Schmitz, T.; Dickschat, J.S.
    Mechanistic investigations on six bacterial terpene cyclases (2016), Beilstein J. Org. Chem., 12, 1839-1850.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.2.3.169

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli BL21 Streptomyces viridochromogenes

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(2E,6E)-farnesyl diphosphate + H2O Streptomyces viridochromogenes
-
 7-epi-alpha-eudesmol + diphosphate
-
 ?
(2E,6E)-farnesyl diphosphate + H2O Streptomyces viridochromogenes DSM 40736
-
 7-epi-alpha-eudesmol + diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Streptomyces viridochromogenes D9XD61
-
-
Streptomyces viridochromogenes DSM 40736 D9XD61
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Streptomyces viridochromogenes

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2E,6E)-farnesyl diphosphate + H2O
-
 Streptomyces viridochromogenes 7-epi-alpha-eudesmol + diphosphate
-
 ?
(2E,6E)-farnesyl diphosphate + H2O no activity with geranyl diphosphate and geranylgeranyl diphosphate. 7-epi-alpha-Eudesmol biosynthesis proceeds via reprotonation of the neutral intermediate hedycaryol Streptomyces viridochromogenes 7-epi-alpha-eudesmol + diphosphate
-
 ?
(2E,6E)-farnesyl diphosphate + H2O
-
 Streptomyces viridochromogenes DSM 40736 7-epi-alpha-eudesmol + diphosphate
-
 ?
(2E,6E)-farnesyl diphosphate + H2O no activity with geranyl diphosphate and geranylgeranyl diphosphate. 7-epi-alpha-Eudesmol biosynthesis proceeds via reprotonation of the neutral intermediate hedycaryol Streptomyces viridochromogenes DSM 40736 7-epi-alpha-eudesmol + diphosphate
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
28
-
 assay at Streptomyces viridochromogenes