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Information on EC 4.1.1.43 - phenylpyruvate decarboxylase and Organism(s) Aspergillus oryzae and UniProt Accession Q2UKV4

for references in articles please use BRENDA:EC4.1.1.43
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EC Tree
     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.43 phenylpyruvate decarboxylase
IUBMB Comments
The enzyme from the bacterium Azospirillum brasilense also acts on some other substrates, including (indol-3-yl)pyruvate, with much lower efficiency. However, it only possesses classical Michaelis-Menten kinetics with phenylpyruvate. Aliphatic 2-oxo acids longer that 2-oxohexanoate are not substrates. cf. EC 4.1.1.74, indolepyruvate decarboxylase.
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This record set is specific for:
Aspergillus oryzae
UNIPROT: Q2UKV4
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The taxonomic range for the selected organisms is: Aspergillus oryzae
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
aro10, phenylpyruvate decarboxylase, ydr380w, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Decarboxylase, phenylpyruvate
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
decarboxylation
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SYSTEMATIC NAME
IUBMB Comments
phenylpyruvate carboxy-lyase (phenylacetaldehyde-forming)
The enzyme from the bacterium Azospirillum brasilense also acts on some other substrates, including (indol-3-yl)pyruvate, with much lower efficiency. However, it only possesses classical Michaelis-Menten kinetics with phenylpyruvate. Aliphatic 2-oxo acids longer that 2-oxohexanoate are not substrates. cf. EC 4.1.1.74, indolepyruvate decarboxylase.
CAS REGISTRY NUMBER
COMMENTARY hide
37289-45-5
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
Phenylpyruvate
Phenylacetaldehyde + CO2
show the reaction diagram
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-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
cf. EC 4.1.1.1
UniProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
a gene disruptant grown with glucose and phenylalanine excrets less than1% phenylethanol into the medium, compared with the wild-type strain
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
expressed at high levels in the presence of exogenous L-phenylalanine
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Masuo, S.; Osada, L.; Zhou, S.; Fujita, T.; Takaya, N.
Aspergillus oryzae pathways that convert phenylalanine into the flavor volatile 2-phenylethanol
Fungal Genet. Biol.
77
22-30
2015
Aspergillus oryzae (Q2UKV4), Aspergillus oryzae
Manually annotated by BRENDA team